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Lenvaxen 4 mg 30 Capsule | Lenvatinib

Product Name: Lenvaxen

Generic: Lenvatinib

Indication: Thyroid Cancer, Kidney Cancer

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Lenvaxen 4 mg (30 Capsule) is a targeted therapy used to treat certain type of metastatic thyroid cancer, advanced renal cell carcinoma with everolimus. It is also used to treat unresectable hepatocellular carcinoma. Lenvaxen is in a class of tyrosine kinase inhibitor works by blocking abnormal growth of cancer cells or slow them.

It is indicated to treat

  • Locally recurrent or metastatic, progressive, radioactive iodine-refractory differentiated thyroid cancer (DTC) in adult patients.
  • In combination with Everolimus to treat advanced renal cell carcinoma (RCC) following one prior anti-angiogenic therapy.
  • First-line treatment of unresectable hepatocellular carcinoma (HCC).
  • Also to treat Endometrial Carcinoma in combination with pembrolizumab.

Dosage and Administration

Patients should continue regular schedule until disease progression or unacceptable toxicity.

  • For differentiated thyroid cancer, recommended dose is 24 mg lenvaxen daily ( 6 capsules of 4 mg) once by mouth.
  • 18 mg of lenvaxen with 5 mg of everolimus daily once by mouth to treat advance renal cell carcinoma.
  • 12 mg of lenvaxen if patient’s weight is more than 60 kg and 8 mg of lenvaxen if patient’s weight is less than 60 kg daily once by mouth to treat hepatocellular carcinoma (HCC).
  • The recommended dose is for Endometrial Carcinoma is 20 mg of lenvaxen in combination with 200 mg of pembrolizumab as an intravenous infusion for every 3 weeks.

Pregnancy and lactation

Findings from animal studies indicates that taking Lenvaxen during pregnancy may harm fetus in the worm. The suggestion is not taking this drug while being pregnant or using proper contraception during this treatment. There are not available data on human that it is harmful or not. But from animal studies, researchers have make an assumption that it may harm.

Breast feeding during treatment with Lenvaxen is not recommended, because breast milk may contain chemical substance of Lenvaxen and harm children.

Side Effects

The most common adverse effects of using lenvaxen are hypertension, cardiac dysfunction, arterial thromboembolic events, hepatotoxicity, renal failure and impairment, proteinuria, diarrhea, fistula formation and gastrointestinal perforation, QT Interval Prolongation, hypocalcemia, reversible posterior leukoencephalopathy syndrome, and hemorrhagic events.

Storage

Store below 30°C in a dry place away from direct sunlight and children.

FAQs about Lenvaxen 4 mg / 10 mg (30 Capsule)

What is the price of lenvaxen 4 mg for 30 Capsule?

The price of lenvaxen 4 mg 30 capsule is $170 and for lenvaxen 10 mg 30 capsule $360.

What should I do if I miss a dose of Lenvaxen?

If you miss a dose or take an overdose do not take double dose in case of missing dose and do not miss the next dose because you have taken overdose. Or immediately consult with your doctor.

See also lenvanix, similar product from Beacon pharmaceutical.

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