Tagrix 80 mg Tablet | Osimertinib

Tagrix 80 mg Tablet is a protein kinase inhibitor, which contains the active ingredient osimertinib. It is used to treat non-small cell lung cancer. Tagrix will work when a test shows that your cancer has certain changes in gene called EGFR(Epidermal Growth Factor Receptor). Your doctor will prescribe Tagrix for you

• as a post surgical treatment (after complete removal of your cancer)
• as a first line treatment for spreading cancer to the other parts of the body or
• if you have been treated your cancer before with other protein kinase inhibitor

Tagrix can be prescribed in combination with other medicines. Such as, pemetrexed and platinum containing chemotherapy as a first-line medicine for your cancer which has spread to other parts of the body. To take Tagrix with other medicine read both leaflet carefully. Otherwise, you may ask your doctor. Afanix and osimert are also used to treat this kind of lung cancer.

How Tagrix 80 mg Tablet works?

Tagrxi works by blocking EGFR and slow down the growth of cancer cells. In addition, it may also help to reduce the size of the tumor and prevent the tumor coming back after surgery.

What should you know before you take Tagrix?

Do not take Tagrix 80 mg Tablet

• if you are allergic to osimertinib or other substance in Tagrix.
• if you are taking St. Johns wort (Yellow star shaped flower used for depression).

Talk to your doctor if you have

• suffered from inflammation of your lungs
• ever had heart disease
• eye problem.

Consult your doctor while taking Tagrix if you have

• sudden difficulty in breathing with cough or fever
• severe peeling of your skin
• persisting fever, bruising or bleeding easily, increasing tiredness, pale skin and infection.

Remember Tagrix has only been approved by FDA for adults. It is not approved for children yet.

Pregnancy information and lactation

If you are pregnant or planning to become pregnant, tell your doctor straight away. Your doctor will suggest you. On the other hand if you are already pregnant talk to your doctor and ask whether you should carry the baby or not. Use effective contraception during taking this medicine. Sometimes oral route contraception may not work if you are taking Tagrix. Ask your doctor to suggest right way of taking contraception. Men and women both are suggested to use contraception because chemical substance of osimertinib also may remain in men’s semen. For

• men, keep using contraception after 4 months of taking Tagrix
• women, keep using contraception after 2 months of taking Tagrix.

Do not breast-feed if you are taking this medicine because it may be harmful for baby.

How to take Tagrix?

Take tagrix according to your prescription. But the recommended dose is 80 mg alone each day. Reduce the dose at 40 mg if you can not take 80 mg. If you can not take 40 mg stop taking and consult with your doctor immediately. It has to be taken orally. Swallow the whole tablet, do not chew or crush it. If you are unable to take it orally, take 50 ml water, crush the tablet into water, make a suspension and drink it. Rinse the glass thoroughly with another 50 ml of water to make sure you have taken all the medicine.

Side Effects Tagrix 80 mg Tablet

Severe side effects

• Sudden difficulty in breathing with cough or bleeding
• watery eyes, sensitivity to light, eye pain, eye redness, or vision changes
• Stevens-Johnson syndrome and toxic epidermal necrolysis
• changes in the electrical activity in the heart
• a blood disorder called aplastic anemia
• A condition in which the heart does not pump enough blood

Common side effects

• Diarrhea
• Skin and nail problems
•  inflammation of the inner lining of the mouth or ulcers forming in the mouth.
• Reduction in the number of white blood cells
• Reduction in the number of platelets in the blood.

Storage

Store the medicine below 25 C and away from children.

Tagrix 80 mg Price

The price of Tagrix 80 mg of a 30 tablets pot is $350.