Eudaxen (Diazoxide 50 mg Tablet)

Eudaxen 50 mg is a treatment option to maintain low blood sugar caused by excessive secretion of insulin in certain conditions, such as insulinoma or congenital hyperinsulinism. Eudaxen works by reducing the release of insulin from the pancreas, which helps patients maintain normal blood sugar. The common side effects experienced by the patients are increased hair growth, nausea, headache, and rapid heartbeat. Regular monitoring is important to manage severe reactions.

Eudaxen is in the class of antihypoglycemic agents. It is approved by the FDA to treat certain low blood sugar diseases caused by excessive insulin. It is a benzothiadiazine derivative, related to thiazide diuretics, without typical diuretic effects.

What is Eudaxen 50 mg tablet used for?

Diazoxide was approved by the FDA for the management treatment of symptomatic hypoglycemia due to hyperinsulinism in adult patients and pediatric patients 4 years of age. A recently extended form of Diazoxide has been approved to treat different indications, which is different from the standard Diazoxide 50 mg formulation.

How does Eudaxen work?

Eudaxen 50 mg tablet raised the blood glucose level primarily by inhibiting insulin release from the pancreas when the body produces too much insulin (causing blood sugar to drop dangerously low). Eudaxen helps reduce insulin output and thus helps raise blood sugar.

What is the dose of Eudaxen tablet?

Eudaxen dosage and administration can be different depending on the patient’s age, weight, and severity of hypoglycemia. The general dosage guideline is below

• In adults: Initial dose is 3 mg/kg/day divided into 2 or 3 doses every 8-12 hours. Typical dose is 3-8mg/kg/day.
• In children/infants: for a newborn baby initial dose is 10 mg/kg/day divided every 8 hours. Typical dose is 8-15 mg /kg/day divided by 8-12 hours.
• The maximum recommended dose is 5.8 mg/kg/day or 535 mg per day.

The exact 50 mg tablet dose for your specific situation should be set by your doctor.

How to take Diazoxide 50 mg?

• Take exactly as your doctor prescribes and follow the label or directions from your healthcare provider.
• If you are taking the suspension form, shake well before each dose and use a proper measuring device.
• Do not use Eudaxen tablet to treat occasional low blood sugar from diet or skipped meals. It is only for specific medical conditions diagnosed by an FDA-approved test.
• Usually, you will be on regular monitoring of blood glucose and possibly other tests while on this medication.
• Administer orally once daily.
• Before initiating the test, fasting plasma glucose and HbA1c.

What are the side effects of Diazoxide medicine?

Common and important side effects include:

• High blood sugar can be serious and may lead to diabetic ketoacidosis in rare cases.
• Fluid retention/edema (swelling of feet, ankles, or face) due to sodium/water retention.
• Increase hair growth (hypertrichosis), especially on the face, back, arms, and legs.
• Nausea, vomiting, stomach pain, loss of appetite, changes in taste.
• Rare but serious: In infants and newborns, the drug has been associated with pulmonary hypertension (a serious lung/heart condition).
• Other lab abnormalities, such as uric acid, changes in platelets.

What should I tell my doctor before taking Diazoxide?

• Any allergy to Eudaxen or related drugs.
• If you have heart disease, kidney problems, fluid retention, edema, diabetes, or pre diabetes, or gout.
• If you are pregnant or plan to become pregnant, or are breastfeeding. Safety in pregnancy and lactation is not established, but results from clinical trials in animals show that it can harm the fetus in the womb or the newborn baby eating breastmilk. Using proper contraception for both male and female partners is advised to avoid unwanted harm.
• Any medications, supplements, or herbal products you take.
• If you are planning to undergo surgery or have an acute illness, or have infections.
• Tell your healthcare provider if you have other problems too.

How to store diazoxide?

Store Eudaxen 50 mg in a cool, dry place away from light and keep the bottle tightly closed. Store the medication at room temperature.

How much does Diazoxide cost in Bangladesh?

Diazoxide 50 mg price in Bangladesh actually depends on available brands and manufacturers. The cost of the whole treatment depends on the required doses and treatment duration. To know the latest price, discuss with the available authorized distributors in Bangladesh.

How long does diazoxide take to work?

Eudaxen (Diazoxide) starts working after one hour of taking the medication and lasts for 8 hours in people with normal kidney functionality. Your doctor will monitor blood sugar responses and adjust the dosing schedule accordingly.

How to buy Diazoxide online?

As Diazoxide is a prescription-only medicine, you cannot directly buy it from any online store. If it is not available in your region, find a manufacturer or authorized distributor and ask them whether they supply it online. Before buying online, make sure safe packaging of the medication and authentic.

What generic brand of Diazoxide is available in Bangladesh?

Everest Pharmaceuticals is manufacturing and supplying generic Diazoxide (Eudaxen) in Bangladesh. Though there are other generic brands are also available.