Caboxen 20 mg (90 Capsules) | Cabozantinib

Caboxen 20 mg (90 Capsules) is used to treat advanced renal cell carcinoma and hepatocellulor carcinoma alone or in combination with other medication. It is a tyrosine kinase inhibitor, works by blocking the abnormal growth of protein that stimulate cancer cells to multiply or spread in other parts of the body. At first it was approved to treat metastatic medullary thyroid cancer and later it got approval for renal cell carcinoma and hepatocellulor carcinoma.

What is Caboxen?

Caboxen is a prescription medication used to treat renal cell carcinoma(RCC) and hepatocellular carcinoma(HCC).It should only be used under the guidance of healthcare professionals.

Caboxen is used when patients are diagnosed with certain types of kidney cancers such as HCC and RCC. It is in a class of tyrosine kinase inhibitors, targets specific cancer cells and blocks their growth.

Ingredient in Caboxen 20 mg

Each caboxen 20 mg drug contains cabozantinib 20 mg, tyrosine kinase inhibitors.

Caboxen 20 mg Tablet

Both, the caboxen 20 mg and caboxen 80 mg come in tablet form. Each box of caboxen 20 and caboxen 80 contains 90 tablets in it.

Caboxen 80 mg

Caboxen 80 mg is the higher dose of caboxen 20 mg. It is suggested when patients need higher dosage to maintain certain medical conditions in kidney cancer like HCC and RCC.

What is Caboxen 20 mg and Caboxen 80 mg used for?-Indications

Caboxen 20 and caboxen 80 is used to treat certain types of cancer such as

• Advanced renal cell carcinoma and hepatocellular carcinoma may be alone or in combination with other immunotherapy.
• Metastatic hepatocellular carcinoma that has spread to other parts of the body especially in the liver.
• It is also used in medullary thyroid cancer that has metastasized or can not be removed by surgery.

Dosage and Administration

• The recommended dose to treat renal cell carcinoma and hepatocellulor carcinoma is 60 mg Caboxen daily without food until disease progression or unacceptable toxicity.
• Stop taking Caboxen at least 28 days before any surgery even dental surgery.
• Do not substitute tablets with capsules.
• Do not administrate Caboxen immediately before or after taking food. You should administrate this drug at least 1 hour before and 2 hours after taking food.
• Take the capsule whole, do not chew or crash.
• For any missing dose or over dose contact with doctor.

How to use Caboxen?

Caboxen is an oral medication that should be taken with an empty stomach. Or at least before one hour of meal and two hours after taking the meal so that food can not absorb the effectiveness of the medicine.

Do not chew, crush the medicine, take the whole medicine and swallow it with water to ensure the effectiveness.

Do not take the caboxen if the patient is allergic to cabozantinib or any other ingredients in the medicine. Patients with fistula or unhealed wound should not use caboxen.

Take precautions before using Caboxen 20 mg and Caboxen 80 mg drug

• Caboxen 20mg can cause a risk of bleeding, especially when used with anticoagulants. Caboxen 20mg should be used with caution because it can cause intestinal perforation and fistula, high blood pressure , proteinuria, liver and thyroid dysfunction.

• Because Caboxen 20mg can slow wound healing, it is necessary to stop using the drug at least 28 days before surgery.
• Note when using medicine for pregnant and lactating women Do not use Caboxen 20mg for this subject.

Side Effects

The most common adverse effects of administrating Caboxen are

• Hypertension and Hypertensive Crisis
• Diarrhea
• Palmar-plantar Erythrodysesthesia
• Proteinuria
• Osteonecrosis of the Jaw
• Wound Complications
• Reversible Posterior Leukoencephalopathy Syndrome
• Hemorrhage
• Perforations and Fistulas
• Thrombotic Events

Others side effects may happen if patients have any serious medical condition before.

Pregnancy and Lactation

It was experienced in animal studies that taking Caboxen during pregnancy may harm the fetus in the worm. It is not recommended to take Caboxen while you are treating with Caboxen or take proper contraception to prevent unwanted pregnancy.

Caboxen contains many chemical substitution, which may be intolerable for children. So breast feeding during taking caboxen is not recommended by doctors. If you have a children and need to take caboxen contact with doctor before taking caboxen.

Caboxen price

Caboxen comes in two variants 20 mg and 80 mg and both cost different. 

caboxen 20 mg price

Caboxen 20 mg price is $250 US dollar in Bangladesh.You can buy caboxen 20 mg online from Onus Pharma. To make your query contact us.

Caboxen 80 mg price

Caboxen 80 mg is $350 US dollars. To buy caboxen 80 mg online contact us.

Caboxen (Cabozantinib price in India)

In india caboxen (Cabozantinib) price is 21200 rupees for 20 mg and 30,000 rupees for 80 mg.

Caboxen (Cabozantinib price in Pakistan)

Caboxen 20 mg price in pakistan is 69,500 Pakistani rupees and caboxen 80 mg price in Pakistan is 97,000 Pakistani rupees.

Storage

Store below 30 degree C to keep it active and effective. Keep it away from children and direct sun light.

FAQs about Caboxen 20 mg (90 Capsules)

What is the price of caboxen 20 mg for 90 Capsules?

The price for Caboxen 20 mg 90 capsules is $350. There is another version of Caboxen is 80 mg, in a 80 mg bottle there are 30 capsules which costs only $ 370.

What are the symptoms of taking overdose of Caboxen?

Symptoms of taking overdose of Cabxen are memory loss, confusion, weight loss.

See also Cabozanix another similar medicine with same generic from Beacon pharmaceutical.