Avalet 20 mg | 28 Tablets | Avatrombopag

Where can I buy Avalet 20 mg online in Bangladesh?

Onus Pharma offers genuine Avalet 20 mg tablets at a competitive price, delivered reliably and securely. Each pack contains 28 tablets, used for the treatment of thrombocytopenia in patients with chronic liver disease or immune thrombocytopenia (ITP).

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• Authentic product sourcing
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What is Avalet 20 mg?

This oral therapy  is the generic version of Avatrombopag. It is used to treat 

• Chronic liver disease associated with thrombocytopenia. Specifically, when previous other thrombocytopenia treatments did not work in patients. 
• Immune Thrombocytopenia (ITP).
• Doctors also may suggest this medication to increase platelet level in other blood disease conditions. 
• Currently, it is being used to treat dengue patients in specific cases when the patient’s platelet level is very low. Like this, it can be used in other blood related diseases when it is necessary to increase platelet level immediately.

What is the active ingredient in Avalet ?

Each tablet contains the active ingredient Avatrombopag. Which is a thrombopoietin receptor agonist. 

How does it work?

It contains the active ingredient Avatrombopag. It works by increasing the production of platelets in the blood cells. Here is the detailed mechanism action 

• Avatrombopag mimics the natural platelet production hormone to produce new platelet cells. This natural hormone is also known as Thrombopoietin. 
• It also binds the thrombopoietin receptor in the surface of large bone marrow cells which produces new platelets. 
• By binding the thrombopoietin receptor it stimulates the system to produce more mature Megakaryocytes ( The large bone marrow cell) in the bone marrow. 
• When the number of Megakaryocytes are increased the number of platelets are also increased naturally. That helps patients to stop bleeding naturally and to increase the number of platelets within a short period of time.

Is this medication a blood thinner?

No. It is not a blood thinner. It is a thrombopoietin receptor agonist. Works by stimulating the bone marrow to produce new platelets in the blood.

Who is the manufacturer of this drug?

Drug international LTD is the manufacturer of Avalet 20 mg (Avatrombopag)

What is Avalet 20 mg used for?

Avalet is indicated to treat specific medical conditions including low platelet count (Thrombocytopenia) Treatment. Here are the primary reasons why it is prescribed

• Primarily it is used to  increase platelet count in chronic liver disease (CLD) before a procedure. Patients who have chronic liver disease often have a sufficient amount of platelets. Which increases the chance of bleeding while proceeding a surgery. Avalet is used to increase the platelets in the patients and reduce the risk of bleeding during surgery.
• It is also used to treat chronic immune thrombocytopenia (ITP) in adults. ITP is an autoimmune disorder, where the immune system attacks itself and destroys platelets. Avalet is used in this case to boost platelets. 

What is the usual dose?

This oral drug can be taken with or without food. The recommended doses to different disease are as below

• To treat chronic liver disease associated with thrombocytopenia, patients should take 60 mg of Avalet daily for 5 days if their platelet count is less than 40 × 10⁹/L. And 40mg daily if platelets count are less than 50X109/L.
• Dosage and administration process can be adjusted according to the registered doctor’s prescription.

How should it be taken?

It is an orally administrable drug.You should take this medication by mouth.

What to do if I miss a dose?

If you miss a dose, try to take it at least 12 hours before the next dose. Otherwise skip the missed dose and consult with your healthcare provider.

Proper administration guidance

This platelet booster medication is usually used under the guidance of a specialist. Below is a general guide on how to use this medication, however, always follow the specific instructions of your doctor or pharmacist.

When to use: It is usually taken once daily. Follow the dosing schedule instructed by your doctor.
Taking the medicine: Take the medication as directed by your doctor, usually with meals or as otherwise directed by your doctor.
Monitoring liver function: While you are taking this drug, your doctor may order periodic tests to check your liver function and adjust your dosage if necessary.
Drug interactions: You should inform your doctor about any other medications or dietary supplements you are taking, including prescription drugs, nonprescription drugs, and supplements. This medication may interact with a number of other medications, so follow your doctor’s instructions to avoid unwanted interactions.
Monitoring and interactions: You should see your doctor regularly to monitor your health and the effectiveness of the drug. Discuss any side effects you experience and ask your doctor about any questions or concerns.

What are the side effects?

Common side effects of this treatment in liver disease cases include

• Pyrexia
• abdominal pain
• nausea
• headache
• fatigue
• and edema peripheral 

The most common side effects for Immune thrombocytopenia (ITP) with Avalet are

• Headache
• fatigue
• confusion
• epistaxis
• arthralgia
• Gingival bleeding 

Are there any risks associated with this treatment?

Yes there are some risks associated with Avalet 20 mg if patients have other critical or non-critical issues.

• Deep vein thrombosis (risk of blood clots)
• Pulmonary embolism (risk of blood clots)
• Liver enzyme elevations
• Thrombocytosis
• Worsening ITP after stopping Avalet

What should I know before taking Avalet ?

Before starting this drug, follow these steps and talk to your doctor:

• Share your medical history: Let your doctor know about any health conditions you have or had in the past, such as liver or kidney disease, chronic illnesses, drug allergies, or platelet-related problems.
• List your medications and supplements: Inform your doctor about all the medicines you’re taking, including prescription and over-the-counter drugs, as well as any vitamins or supplements. This helps prevent any unwanted interactions.

Can pregnant or breastfeeding women take this medication?

Pregnant women should be aware of the potential harm of taking Avalet during pregnancy because it can harm the fetus. It is also recommended for those women who are feeding breast to their children that active ingredients in Avalet can harm children. In both cases patients should follow the registered doctor’s advice before taking this drug.

Are there any drug interactions?

Yes there are some drug interactions of this medication are as follow

• Strong CYP3A inducers (Rifampin, Carbamazepine, Phenytoin, St. John’s Wort)
• Strong CYP3A inhibitor (Warfarin, Aspirin, Clopidogrel)

What is the price of Avalet 20 mg in Bangladesh?

Avalet 20 mg price in Bangladesh is $120 for 28 tablets package. There are also 10 tablet packs available. For the latest Avalet 20 mg pricing, reach out to us. Prices may differ by country, such as

• 700 in China
• 2.5 million VND in Vietnam
• 8500 rupees in India
• 4000 Turkish lira in Turkey
• And 28,200 rupees in Pakistan.

If you are looking for the price in your region contact us to know

• WhatsApp: +8801540071497
• Scan the QR code to connect WeChat 

Is it available over the counter?

No. Avalaet is a prescription medication and it is not available over the counter. You need a valid prescription to buy this medication whether from retail pharmacy or online pharmacy. 

How much does Avalet 20 mg cost in Bangladesh?

In Bangladesh, a 28-tablet pack of Avalet 20 mg costs approximately 10,000 BDT for authentic medication. It also has a 10-tablet strip, which is priced lower.

How effective is it?

It has shown very good response in treating thrombocytopenia associated with chronic liver disease and immune thrombocytopenia. The response rate was 66% for CLD and 70%-80% in immune thrombocytopenia. Individual results can vary depending on the patient’s health condition.

How long does it take to work?

• In patients with chronic liver conditions, platelet levels generally begin to increase within 4–5 days

For Immune thrombocytopenia (ITP)

• Platelets count begins to rise in 1-2 weeks. 
• It may take several weeks to get a stable response depending on individuals. 

When should I discontinue ?

If you face any severe adverse reaction or intolerable toxicity then you should stop taking Avalet.

Elopag is also used to treat other types of thrombocytopenia.