Nexataf 25 mg (Tenofovir Alafenamide)

Nexataf 25 mg (Tenofovir Alafenamide): Next-Generation Treatment for HIV-1 and Chronic Hepatitis B

Nexataf 25 mg is an advanced antiretroviral medication containing Tenofovir Alafenamide. It is a crucial component in the treatment of HIV-1 infection and chronic Hepatitis B virus (HBV) in adult patients. Compared to older versions, this formulation delivers effective concentration at lower doses, significantly reducing kidney and bone-related side effects.

Manufactured with excellence by Everest Pharmaceutical, Nexataf 25 mg is globally accessible through Onus Pharma, a trusted bridge maker between the medication and users.

Therapeutic Use and Mechanism of Action

Why is it used?

It is used to treat Hepatitis B virus (HBV) infection in adults and children above 12 years of age or body weight ≥35 kg with comprehensive liver disease. It is also used to treat HIV-1 infections with other antiretroviral agents in adults and children above 12 years of age with the above-mentioned condition.

How does Nexataf 25 mg work in patients with HBV and HIV-1 infections?

Nexataf 25 mg is a prodrug that remains in an inactive form but gets activated when inside the body. It works by blocking an essential enzyme called reverse transcriptase, which is responsible for viral replication in both HBV and HIV-1. Specifically, tenofovir diphosphate blocks reverse transcriptase in HIV-1 and blocks HBV reverse polymerase in HBV, helping to reduce viral replication from RNA into DNA.

Dosage and Administration Guidelines

The recommended dose for Nexataf 25 mg is 25 mg once daily for both HBV and HIV-1 patients, with or without food, as recommended by the healthcare provider.

• Take Nexataf 25 mg tablets at the same time every day.

• Swallow the whole tablet with water; do not crush it.

• Do not take grapefruit or its juice immediately before or after taking the drug.

• HIV-1-infected patients may receive recommendations to use Nexataf 25 mg in combination with other medications.

Safety Profile and Contraindications

Common Side Effects Experienced by Patients

Though this medication is well-tolerated, common side effects experienced by patients include headache, nausea, fatigue, diarrhea, and abdominal pain. These effects are self-limiting, meaning they typically resolve over time. However, patients with pre-existing chronic liver disease may experience severe side effects, making proper diagnosis and medical attention necessary before starting this medication.

Who Should Avoid Taking Nexataf 25 mg (Tenofovir Alafenamide)?

Patients who are hypersensitive to this medication or any ingredients in it should avoid it. It is also contraindicated with strong CYP3A inducers like rifampin, carbamazepine, and St. John’s Wort, as they can reduce the drug’s effectiveness. Patients with severe renal impairment should also avoid this medication.

Essential Precautions Before Using This Medication

Precautions can ensure your treatment journey is smooth and easier. The following should be addressed before taking Nexataf 25 mg:

• Renal Function: Although Tenofovir Alafenamide has less renal toxicity than earlier versions, kidney function monitoring and necessary kidney tests should be done, especially in patients with pre-existing kidney problems.

• Liver Health: Liver function monitoring and necessary liver tests must be done before starting this medication.

• Drug Interactions: Inform your doctor about all medications, as this drug may interact with anticonvulsants, rifampin, and other drugs that affect drug-metabolizing enzymes.

• Bone Health: Bone health monitoring should be considered in patients with pre-existing bone health issues.

• Pregnancy/Breastfeeding:

  • It is not recommended for pregnant women as it can harm the fetus.

  • Breastfeeding women are also not recommended to take this drug.

  • Proper contraception is advisable for women and men taking this drug to avoid unwanted health risks.

Manufacturer, Supplier, and Global Access

Manufacturer and Supplier Information

Everest Pharmaceutical has demonstrated its efficacy in making anti-viral medication, and Nexataf 25 mg is another manufacturing excellence. This GMP-certified pharmaceutical maintains all WHO and FDA criteria, ensuring the medication is high-quality, has fewer side effects, and is affordable. Onus Pharma is a trusted partner, ensuring the availability and worldwide supply of this significant anti-viral drug.

Is Nexataf 25 mg (Tenofovir Alafenamide) Globally Accessible?

Yes. This antiretroviral medication is globally accessible, where it is not restricted by the local government. You can collect this medication with a valid prescription provided by a licensed healthcare provider.

Why Choose Onus Pharma?

• On-time worldwide delivery.

• Connecting patients with manufacturers for genuine medicine.

• 24/7 customer service facilities.

• Providing a safe payment gateway.

• Focus on building trust and customer satisfaction.

Generic Tenofovir Alafenamide in Bangladesh

The unit price of Nexataf 25 mg in Bangladesh is $2 USD.

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Disclaimer: This content provides only general information; it does not constitute medical advice. This information only reflects general information on the package body and details the process of accessing the medication for patients and healthcare providers.