Daclaxen 60 mg (Daclatasvir)

Daclaxen 60 mg is a direct-acting antiviral (DAA) medication containing the active ingredient daclatasvir. It is an essential component of curative therapy used to treat chronic Hepatitis C virus (HCV) infection in adult patients.

Manufactured by Everest Pharmaceuticals, Daclaxen 60 mg is designed to offer a high sustained virologic response (SVR) rate, particularly when used in combination with Sofosbuvir.

Mechanism of Action and Therapeutic Use

Why is this direct-acting antiviral medication used?

This direct-acting anti-viral medication is used to treat chronic hepatitis C in combination with sofosbuvir in adult patients with compensated cirrhosis and without cirrhosis. In combination treatment, it blocks the viral replication in patients’ bodies and has potential efficacy in treating multiple genotypes of HCV.

How does it work in an infected liver with the Hepatitis C virus?

The active ingredient, daclatasvir, works by inhibiting the NS5A protein in the infected liver. The NS5A protein is essential for viral RNA replication and assembly in the body. By blocking this protein, Daclaxen 60 mg helps stop the virus from multiplying and spreading within the body.

Dosage and Administration

How many of Daclaxen 60 mg (Daclatasvir) tablets should be taken for HCV treatment?

The general recommended dose is 60 mg daily once with or without food as prescribed by the doctor. It may be suggested to take the medication for up to 12 weeks, but the duration may change according to the patient’s medical history, genotype, and cirrhosis status. Dosage adjustment may be required depending on the patient’s tolerability, and a missed dose should be taken as soon as possible.

Safety, Reactions, and Drug Interactions

What are the common reactions of the medication?

The common reactions of the medication experienced by patients were nausea, fatigue, headache, diarrhea, and abdominal pain. Though generally well-tolerated, in some cases, Hepatitis B reactivation may happen if the patient was diagnosed with HBV before. Other common or adverse reactions may depend on the patient’s metabolism, absorption capability, and medical condition.

What Should You Avoid While Taking Daclatasvir?

Daclatasvir may interact with some CYP3A enzymes. Avoid the following:

• CYP3A Inducers (may reduce the effect of the medication): Rifampin, Carbamazepine, Phenytoin, and St. John’s Wort.

• CYP3A Inhibitors (may increase the level of daclatasvir): Ketoconazole, Clarithromycin, and Ritonavir-boosted protease inhibitors.

Who should not use Daclaxen 60 mg (Daclatasvir)?

• Patients who are allergic to Daclaxen 60 mg or have an allergy to any other medications.

• Pregnant women are not recommended to take it, as there are not enough studies that prove it is safe.

• Breastfeeding women also should not use this; breast milk may contain ingredients that may harm infants.

• Patients with serious kidney or pre-existing liver problems are generally not advised to take this medication.

Precautions Before Taking This Drug

Before starting Daclaxen 60 mg, you must inform your doctor about the following:

• All your existing health conditions.

• The other medications you are taking, including herbal supplements.

• If you have ever gone through any critical surgery.

• Your kidney or liver function status.

• You must reduce the consumption of alcohol and stop smoking.

Manufacturer Information & Global Access

Daclaxen 60 mg is manufactured and marketed by Everest Pharmaceuticals, a renowned pharmaceutical company for its excellence in the oncological and anti-viral sector.

What is the price of Daclaxen 60 mg (Daclatasvir), and how can I access this drug globally?

The price is determined by the manufacturer and varies according to geo-location. You can access this drug globally through Onus Pharma, a trusted supplier of oncology and anti-viral medicines. Onus Pharma bridges Daclaxen 60 mg and users through international delivery partners, ensuring on-time delivery and affordable charges. To know the exact price of Daclaxen 60 mg in Bangladesh, contact their customer service, which is open 24/7.