Briganix 180 mg Brigatinib

What is Brigatinib used for?

Briganix 180 mg (Brigatinib) is an FDA-approved treatment for anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC). It is a multi-tyrosine kinase inhibitor targeting ALK, ROS1, IGF-1R, and EGFR deletions. It works by inhibiting ALK, which signals cancer cells to grow and spread to other parts of the body.

Manufacturer: Briganix 180 mg is produced by Beacon Pharmaceuticals, a leading pharmaceutical company in Bangladesh.

Brigatinib 180 mg Dosage

• To treat ALK-positive non-small cell lung cancer, patients should take 90 mg daily by mouth for 7 days.
• If patients can tolerate 90 mg, they should increase to 180 mg daily until disease progression.
• If the treatment is interrupted for more than 14 days, restart with 90 mg for 7 days before returning to the previously tolerated dose.
• Once discontinued, do not increase the dose again. If patients cannot tolerate 60 mg daily, treatment should be discontinued permanently.

How is Brigatinib administered?

When you are using any medicine, you should know its proper use and application. Proper administration helps prevent adverse side effects and avoids treatment disruptions. Follow the administration guidelines below.

• Do not take the medicine more or less of it. Both overdose and missed doses can negatively impact your treatment. If you miss a dose, and you remember it later, inform your doctor instead of taking over overdose on your own.
• Read the instruction manual inside the box whole to understand the user mechanism of the medicine. If you do not understand any part of the manual, call your doctor and ask about it. It should be mentioned how you can take the medicine.
• Take the medicine with or without food as your doctor prescribes you to take it.
• Do not chew or crush the tablet. Swallow the tablet whole with a full glass of water or another liquid that does not interact with the medication.
• You should not consume any form of alcohol, smoke cigarettes, or engage in other sort of bad habit during the treatment.
• Ask your doctor to monitor your health regularly until the disease is completely treated.
• Share everything about your daily life habits with your doctor. They will suggest you what to do and what not to do.

What are the side effects of Brigatinib?

Side effects are a common part of any medication. Every medicine has side effects, ranging from mild to moderate, depending on the patient’s health condition and other factors.

• If you are using any lung cancer medicine, you should always check your lung health before and after taking lung cancer medicines.
• Lung cancer medications may also affect vital organs such as the kidneys, liver, and heart. Regular monitoring is essential.
• Patients who have previously used Briganix for ALK+ NSCLC have experienced mild to moderate side effects.
• yellowing of your skin or the white part of your eyes.

• dark or brown (tea color) urine.
• nausea or vomiting.
• pain on the right side of your stomach.
• bleed or bruise more easily than normal.
• itchy skin.
• decreased appetite.
• feeling tired.

These are mild to moderate side effects reported by patients taking Brigatinib. However, other side effects may also occur, and data may be limited.

To know more, ask your doctor what are other side effects and how to adjust them with this medicine.

Do not forget to inform your doctor if you are getting any side effects that you can not tolerate. The doctor may modify your dose or stop the medicine until the side effects get better. (ref: Drug bank)

Brigatinib 180 mg price in Bangladesh

The current price of a 30-tablet pack of Briganix 180 mg is $650 in Bangladesh. The price of any medication may change depending on the pharmaceutical company. Our customer service team is always ready to assist with your queries.

Pregnancy and Lactation

• Animal studies suggest that lung cancer targeted therapy may harm the fetus during pregnancy. Pregnant patients should avoid this drug, or they should use proper contraception while taking this medication.
• During lactation, breastfeeding should be avoided, or mothers should discontinue the medication.
• For any other clinical instruction, patients must consult with their doctors.

 What are the Drug Interactions of Brigatinib?

Drug interaction can hamper your treatment journey. Brigatinib should not be used with other medications unless prescribed to reduce toxicity. And there are some specific medicines that can interact with this medication.

• If you are using any antibiotics, vitamins, anti-virals, or medicines, inform your doctor before taking the drug.
• If you have recently taken or plan to take a vaccine, inform your doctor, as they cannot be administered simultaneously.
• Also, inform your doctor if you are taking any medicines for other vital organs of your body. Your doctor will tell you which medicine to take and which one to avoid.

How to store Brigatinib?

• Keep this medicine below 25 °C, away from children and direct sunlight. Make sure the safe store of medicine. Because it is expensive and it may cause loss of your health and money.
• Or if children take this by mistake, it can cause harm to them. Be careful about the storage of the medicine. You can not return damaged medicine caused by you to us.

Frequently Asked Questions (FAQs)