Trifluxen (Trifluridine 15 mg and Tipiracil 6.14 mg)

Trifluxen (Trifluridine 15 mg and Tipiracil 6.14 mg) is a combined dose used to treat metastatic colorectal cancer and metastatic gastric cancer in adult patients.

How to use this combination dose to treat stomach cancer?

The combination dose of Trifluridine and Tipiracil comes as a tablet, and it is taken by mouth twice a day with food. It is administered in a 28-day cycle: days 1, 2, 3, 4, and 5, followed by a 2-day break, then days 8, 9, 10, 11, and 12 of the 28-day treatment cycle.

• This cycle may be repeated depending on the effectiveness of the treatment and side effects experienced by the patients. 
• Take the medication at the same time every day. 
• Follow the instructions on the prescription strictly, and ask your doctor or health care provider if you do not understand any part of the prescription.
• Swallow the whole tablet with water.
• Take the exact dose as it is prescribed. Do not take more or less.
• Your doctor may permanently stop or decrease the dose of Trifluridine and Tipiracil depending on the side effects you experience. Tell your doctor what you feel during the treatment. Do not stop taking the medication without your doctor’s permission.
• Wash your hands after taking the medication. If it comes into contact with other people, tell them also to wash their hands or to use latex hand gloves.

What are the side effects of Trifluxen Tablet?

Trifluridine and Tipiracil can cause side effects that can be severe. Tell your doctor if these symptoms do not go away:

• Nausea
• Vomiting
• Stomach pain
• Hair loss
• Constipation
• Change in taste
• Mouth sore 
• Swelling inside the mouth
• Lack of energy 
• Muscle or bone pain
• Headache

Some side effects can be serious. It is important to inform your doctor if any of these symptoms exist.

• Shortness of breath
• Pale skin
• Chest pain
• Pain with deep breathing
• Coughing up blood
• Unusual bleeding or bruising.
• fever, body aches, chills, or other signs of infection

This is not the complete list of side effects of Trifluridine and Tipiracil. Tell your doctor if you see other side effects.

What precautions should I follow?

• Tell your doctor if you are allergic to Trifluxen or any of its ingredients. Ask your doctor for the list of ingredients in Trifluxen.
• Tell your doctor if you are taking any prescription, nonprescription, nutritional supplements, or herbal products.
• Tell your doctor if you ever have low white and red blood cells count, bleeding problems, liver and kidney disease.
• Tell your doctor if you have had any surgery, including dental surgery, before taking the medication.
• Tell your doctor if you are pregnant or planning to become pregnant. Trifluridine and Tipiracil may cause harm to your unborn baby. 
• Also, tell your doctor if you are breastfeeding or planning to breastfeed. It can cause harm to your children.