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Palbonix 100 mg Price | (21 Capsules) | Order Online
Product Name: Palbonix
Generic : Palbociclib
Indication : HR-positive and EGFR-2 negative advance breast cancer
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Palbonix 100 mg is a prescription anti-cancer medication used for the treatment of Hormone Receptor (HR)-positive, Human Epidermal Growth Factor Receptor 2 (HER2)-negative advanced or metastatic breast cancer.
As a high-quality generic Palbociclib, Palbonix acts as a CDK4/6 inhibitor. It works by blocking cyclin-dependent kinases, proteins that enable cancer cells to divide and grow. By inhibiting these proteins, Palbonix slows down cancer progression and improves survival rates.
Price & Availability
Buy generic Palbociclib online securely through Onus Pharma. We offer competitive pricing and reliable international shipping.
| Region | Price | Shipping Time |
| Turkey | 10,000 Turkish Lira | 5-7 Days |
| Global/USA | Contact for Quote | Variable |
Ready to Order? Get the best Palbonix 100 mg price today. Contact Onus Pharma for secure processing and fast worldwide delivery.
Medical Uses & Mechanism
Palbonix 100 mg is indicated for the treatment of HR-positive, HER2-negative metastatic breast cancer in adult patients. It is typically prescribed in combination with:
An Aromatase Inhibitor: For postmenopausal women as initial endocrine-based therapy.
Fulvestrant: For patients whose disease has progressed after prior endocrine therapy.
How it Works: The drug targets the cell cycle machinery. Inhibiting CDK4 and CDK6, it prevents cancer cells from moving from the G1 phase to the S phase of cell division, effectively halting tumor growth.
Dosage & Administration
Important: Palbonix 100 mg is often used as a dose reduction step for patients who cannot tolerate the standard 125 mg starting dose.
Standard Dosing Schedule:
Starting Dose: 125 mg orally once daily for 21 consecutive days, followed by 7 days off (28-day cycle).
First Dose Reduction: 100 mg orally once daily.
Second Dose Reduction: 75 mg orally once daily.
If a patient cannot tolerate the 75 mg dose, treatment should be discontinued.
Instructions for Use:
Swallow Whole: Take the capsule whole with water. Do not chew, crush, or open it.
Consistency: Take it at the same time each day, with or without food.
Missed Dose: Do not take an extra dose to make up for a missed one. Resume the schedule the next day.
Dietary Warning: Do not consume grapefruit or grapefruit juice while on this medication, as it increases drug toxicity.
Safety Information
1. Precautions & Warnings
Lung Health: Monitor for symptoms of interstitial lung disease (ILD) or pneumonitis. These are potentially life-threatening conditions requiring immediate medical attention.
Blood Monitoring: Your doctor will perform blood tests every 3 weeks for the first 3 months (and monthly thereafter) to check for Neutropenia (low white blood cell count) and liver function.
Infection Risk: Report any fever or signs of infection to your doctor immediately.
Lifestyle: Stop smoking and avoid alcohol to support lung health and immune function.
2. Pregnancy & Breastfeeding
Pregnancy: Palbonix can cause fetal harm. Do not conceive while taking this drug. Use effective contraception during treatment and for at least 3 weeks after the last dose.
Breastfeeding: Do not breastfeed during treatment and for 3 weeks after the final dose.
3. Drug Interactions
Always inform your doctor of other medications you are taking. Avoid live vaccines and drugs such as:
Antibiotics: Clarithromycin, Telithromycin
Antifungals: Ketoconazole, Itraconazole
Other: Ritonavir, Grapefruit juice, St. John’s Wort
Side Effects
While effective, Palbonix 100 mg may cause side effects. Most are manageable with medical support.
Common Side Effects:
Low white blood cell counts (Neutropenia, Leukopenia)
Fatigue and weakness
Nausea, vomiting, and diarrhea
Hair thinning or loss (Alopecia)
Mouth sores (Stomatitis)
Anemia (Low red blood cell count)
Serious Side Effects:
Hypertension: Monitor blood pressure regularly.
Pulmonary Embolism: Watch for shortness of breath or chest pain.
Severe Infections: Due to lowered immune response.
Storage
Store below 30°C (86°F).
Keep in a dry place away from direct sunlight.
Keep out of reach of children.
Frequently Asked Questions (FAQs) About Palbonix
Q: Why is Palbonix so much cheaper than Ibrance?
A: Palbonix is a generic version of Palbociclib. Unlike the branded medication (Ibrance), which includes high costs for research, development, and marketing, generic manufacturers like Beacon Pharmaceuticals only pay for production. This allows Palbonix to be sold at a significantly lower price (approx. $340 USD) while maintaining the same active ingredient and therapeutic effect.
Q: Can I buy Palbonix 125 mg online in the USA or Turkey?
A: Yes, you can order Palbonix online through Onus Pharma. We specialize in shipping hard-to-find oncology medications to patients worldwide, including the USA, Turkey, Pakistan, and Uzbekistan.
Q: What is the current price of Palbonix 125 mg?
A: Prices may vary slightly due to currency exchange rates, but the estimated price for Palbonix 125 mg is $340 USD (approx. 11,800 TRY or 95,000 PKR). Please contact us for the most up-to-date pricing and shipping quotes.
Q: Do I need a prescription to order Palbonix?
A: Yes. Palbonix is a prescription-only medication. You must provide a valid prescription from a licensed oncologist to purchase this drug from Onus Pharma.
Q: Is Palbonix (Generic Palbociclib) as effective as the brand name?
A: Yes. Palbonix contains the same active ingredient (Palbociclib) in the same strength (125 mg, 100 mg, or 75 mg) as the branded version. It works in the exact same way to inhibit CDK4/6 proteins and slow cancer cell growth.
Q: Who manufactures Palbonix?
A: Palbonix is manufactured by Beacon Pharmaceuticals, a leading oncology drug manufacturer in Bangladesh. Beacon produces medications in facilities that adhere to global standards, including US FDA and WHO GMP (Good Manufacturing Practice) guidelines.
Q: Is it safe to order cancer medications from Bangladesh?
A: Yes, provided you order from a licensed and reputable distributor like Onus Pharma. We ensure that the medication is sourced directly from the manufacturer (Beacon Pharmaceuticals) and shipped under proper temperature-controlled conditions to maintain its efficacy.
Q: How long does shipping take to the USA or Turkey?
A:
Turkey: Estimated delivery is 5–7 business days.
USA & Global: Delivery times vary by location but typically range from 7–14 business days.
Uzbekistan & Pakistan: Fast shipping options are available.
Q: Will I have to pay customs duties?
A: Customs regulations vary by country. While we handle the logistics to ensure smooth delivery, any local import duties or taxes are the responsibility of the buyer. We can assist you with the necessary documentation for a “personal use” import, which is often permitted for serious medical conditions.
Q: What if my dosage changes?
A: Palbonix is available in 125 mg, 100 mg, and 75 mg strengths. If your doctor lowers your dose to manage side effects, simply contact us to order the new strength for your next cycle.
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