Palbocent 125 mg Capsule | Buy Generic Palbociclib Capsule Online

Product Name: Palbocent

Generic: Palbociclib

Indication : Hormone positive metastatic breast cancer

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Why is Palbocent 125 mg Capsule ( Generic Palbociclib)  used?

Palbocent 125  mg Capsule (generic palbociclib) is an FDA-approved initial treatment option for certain hormone receptor-positive and metastatic breast cancer in combination with other drugs. It is also used to treat human epidermal growth factor receptor-2 (EGFR-2) negative metastatic breast cancer in combination with

  • An aromatase inhibitor in postmenopausal women as initial endocrine-based therapy; or
  • Fulvestrant in women with disease progression.

It works by inhibiting cyclin-dependent kinase (CDK4/CDK6) protein. By blocking those protein it reduces the proliferation of cancer cells in patients and slows down the cancer growth.

Active Ingredient in Palbocent 125 mg

Each 125 mg capsule contains the active ingredient Palbociclib 125 mg.

How to use Palbocent 125 mg Capsule?

The general schedule of palbocent is daily once for the first 21 days and then 28 days cycle. This is an oral medicine, the patient can administer this medicine with or without food according to the doctor’s suggestion. General doses and modifications are as follows

  • First dose 125 mg daily once by mouth until disease progression
  • First reduction is 100 mg daily once by mouth until disease progression
  • Second reduction is 75 mg daily once by mouth until disease progression

The patient should discontinue this medicine if they can not take 75 mg of palbocent daily. To change their dosage and administration, they must consult with their doctor. Exception administration may happen depending on patients situation.

Proper Use

Take the medicine as prescribed in the prescription. Do not take more or less of it; it can cause severe side effects. There are also other administration guide let’s have a look. Remember, these administration guides are only for general use. To know the exact administration, ask your health care professional.

  • You will find an instruction paper inside the box for patients. Read that carefully to understand the process of using this medicine. If you do not understand any part of this instruction, consult with your doctor.
  • Swallow the whole tablet with water; do not crush or chew it.
  • Take the same dose every day at the same time. Do not miss a dose or take an overdose.
  • Do not drink grapefruit or its juice while taking this medicine.

What should I know before taking Palbocent 125 mg Capsule?

Precautions can save you from adverse side effects. You should take some precautions before you take the medication to treat metastatic breast cancer locally or advanced.

  • The doctor may do a blood test every 3 weeks for first 3 month and once in a month after 3 months to monitor liver functions. Other tests might be done if necessary to monitor your progression and keep you safe from severe side effects.
  • Inform your doctor if you feel any side effects that you can not tolerate anymore.
  • The medicine may cause interstitial lung disease or pneumonitis. These are life threatening condition and need immediate medical action.
  • Stop taking alcohol and smoking, these damage your lungs and strengthen cancer cells to spread to other parts of the body.
  • Make a balanced diet and a healthy daily routine to keep yourself mentally and physically strong. You can meditate, it keeps your mind fresh and strong, and increases your fighting capability in any odd situation.
  • Tell your doctor right away if you have liver disease, kidney disease, a heart problem, or if you had a stroke before.
  • Tell your doctor if you are taking any antibiotic, vitamin, or other medicine that interacts with this drug.

Palbocent uses in Pregnancy and Lactation

Pregnancy is not safe during this treatment. Follow the instructions in pregnancy &  lactation

  • Do not conceive a baby while taking this medication.
  • Using proper contraception for both males and females is recommended.
  • If you are already pregnant and the doctor prescribed you this medication, consult with the doctor.
  • Chemical substances in the medication can remain for months. Do not get pregnant immediately after discontinuing the drug.
  • Do not breastfeed during the treatment. It will harm your children. 
  • Consult your doctor after discontinuing the medication to start breastfeeding.

Drug interaction

Drug interaction can reduce the strength of the medicine or may cause serious side effects that can lead to death. Some drugs can interact with sotorasib, which are mentioned below. There might be other drugs that also interact with this drug; for more information, ask your health care professionals.

  • Abemaciclib
  • Adenovirus Vaccine Type 4, Live
  • Aluminum Hydroxide
  • Aluminum Phosphate
  • Axitinib
  • Brigatinib
  • Ceritinib
  • Cholera Vaccine
  • Cobimetinib
  • Crizotinib
  • Dasatinib
  • Esomeprazole
  • Ivosidenib
  • Neratinib
  • Smallpox Monkeypox Vaccine
  • Typhoid Vaccine
  • Varicella Virus Vaccine
  • Yellow Fever Vaccine
  • Mavacamten
  • Measles Virus Vaccine, Live
  • Mumps Virus Vaccine, Live
  • Rubella Virus Vaccine, Live
  • Bacillus of Calmette and Guérin Vaccine, Live
  • Dengue Tetravalent Vaccine, Live
  • Lonafarnib

Palbocent 125 mg Side Effects

Every medicine has side effects, and sometimes itcan become deadly. If you feel any of the side effects mentioned below, immediately call your doctor. They will monitor your health condition and suggest other medicines to adjust side effects. Here are the most common side effects

  • Hypertension and Hypertensive Crisis
  • Diarrhea
  • Palmar-plantar Erythrodysesthesia
  • Proteinuria
  • Osteonecrosis of the Jaw
  • Wound Complications
  • Reversible Posterior Leukoencephalopathy Syndrome
  • Hemorrhage
  • Perforations and Fistulas
  • Thrombotic Events

Other side effects may happen if patients have any serious medical conditions before.

Adverse side effects experienced by women are

  • WBC decreased,
  • Neutrophils decreased,
  • Neutropenia,
  • Platelets decreased,
  • infections,
  • AST increased,
  • ALT increased,
  • Leukopenia,
  • Fatigue,
  • Nausea,
  • Hair loss,
  • Inflammation of the mouth and lips,
  • Diarrhea,
  • Anemia,
  • Rash,
  • Weakness/lethargy,
  • Vomiting,
  • Thrombocytopenia,
  • Dry skin,
  • Fever.

Storage

Store it below 30 degrees C, away from children and direct sunlight.

Palbocent 125 mg price in India

In India, Palbocent 125 mg (generic palbociclib) costs only 7500 INR, which can be changed at any time. To know the exact price, contact us.

Palbocent 125 mg price in Pakistan

Palbocent 125 mg price in Pakistan is 23,000 Pakistani rupees.

Frequently Asked Questions About Palbocent 125 mg

What special diet should I follow while taking Palbocent 125 mg capsule?

There is no special diet for this medication. But some foods can contradict the drug, so try to avoid those foods. Generally, star fruits, Pineapple, and grapefruits are not allowed with the drug.

What if I take an overdose or miss a dose?

Do not take a double dose if you miss your previous dose, or do not miss the next dose if you take an overdose. In case of overdose, if any toxicity or change happens,s contact your doctor immediately.

Disclaimer: This information is for general purposes only. Please consult your doctor before using any medication.

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