Olaparib 150 mg tablet (Olanib)

Olaparib 150 mg tablet (Olanib) is a targeted cancer therapy approved by the FDA. It helps treat ovarian, breast, prostate, and pancreatic cancers linked to certain genetic mutations like BRCA or HRD. By blocking a key protein that cancer cells use to repair themselves, it slows their growth and helps control disease progression.

Indications for Using Olaparib 150 mg Tablet

• Olaparib 150 mg (Olanib) is prescribed as a maintenance therapy for adults with BRCA-mutated advanced ovarian, fallopian tube, or primary peritoneal cancer after a good response to platinum-based chemotherapy.
• It may be used alone or in combination with Bevacizumab for patients whose cancer shows HRD-positive status.
• The medicine is also used in HER2-negative, BRCA-mutated breast cancer, metastatic pancreatic cancer, and metastatic castration-resistant prostate cancer (mCRPC) linked to HRR gene mutations.

Olaparib 150 mg Tablet Uses and Dosage Information

• The usual dose of Olanib tablet is 300 mg (two 150 mg tablets) taken twice daily, with or without food.
• Dosage may vary depending on your cancer type and tolerance.
• Take the tablets whole with water — do not crush or chew them.
• If you experience side effects or miss a dose, contact your doctor immediately.
• Avoid grapefruit or Seville orange products during treatment.

Use the medicine properly to get the best result

• Take the medicine as exactly prescribed by your doctor until disease progression or unacceptable toxicity. 
• If you can not tolerate general doses of the drug, inform your doctor, who may reduce your doses or suggest other medicines to lower the side effects.
• Take the whole medicine with water. Do not chew or crush the tablet; swallow it whole with sufficient amounts of water.
• You may take the medicine with or without food.
• If you have experienced hormone receptor-positive breast cancer, you should continue hormone medicine and consult your doctor.
• Do not eat grapefruit, Seville orange, or their juice with the medication.

Olaparib Tablet Drug Interaction

Avoid using this medication with live vaccines (like yellow fever, varicella, or typhoid) and certain antifungal or antibiotic medications that affect liver enzymes.

Always inform your doctor about all other medicines, supplements, or herbal products before starting treatment.

Olaparib Tablet Uses in Special Cases

Before taking Olanib 150 mg tablet, tell your doctor if you have any allergies, heart, liver, kidney, or lung problems.

It should not be used during pregnancy or breastfeeding as it can harm the baby. Both men and women should use effective contraception during and after treatment.

This medicine is not approved for use in children under 12 years of age.

Tell your doctor about Other medical problems

• Liver disease
• Heart attack or heart failure history in the previous.
• Kidney disease
• Eye vision problem
• Lung disease and
• Bone marrow problem

What are the most common side effects of Olaparib?

This is a list of common side effects that do not include all.

• Black tarry stools
• Bladder pain
• Bleeding gums
• Cloudy urine
• Body aches or pain
• Chest pain
• Cough producing mucus
• Diarrhea
• Difficulty in urination
• Irregular heartbeat
• General feeling of discomfort or illness
• Joint pain
• Loss of appetite
• Loss of voice
• Lower back pain
• Nausea
• Red spot on the skin
• Runny or stuffy nose
• Sore throat

Precautions should be taken for the following medical conditions

• Myelodysplastic Syndrome/Acute Myeloid Leukemia (MDS/AML) occurred in less than 1.5% of patients who have taken Olaparib (Lynparza), and the majority of the events had a fatal outcome. Monitor patients for hematological toxicity at baseline and monthly thereafter. Discontinue if MDS/AML is confirmed. 
• Less than 1% of the patients treated with Lynparza developed pneumonitis. Interrupt the treatment if pneumonitis is suspected and discontinue if it is confirmed.
• This drug can cause fatal harm; advise the patients about the potential risk to the fetus and to use effective contraception.
• Venous thromboembolic events, including pulmonary embolism, occurred in 7% of patients with mCRPC. Monitoring is necessary when it is detected.

Olaparib 150 mg Tablet Price in Bangladesh

Olaparib as Olanib 150 mg is available in many countries, but how much it costs depends on local healthcare systems, insurance, and whether a branded or generic product is supplied. In the UK, access is often shaped by NHS or private care arrangements; in India and Bangladesh, quality generics are commonly available and can reduce out-of-pocket expenses; in Turkey’s availability and patient costs vary with hospital procurement and insurance. If affordability is a concern, talk with your oncologist or pharmacist about whether a licensed generic is appropriate for you and how to obtain it safely.

Frequently Asked Questions about Olaparib

How long can you take Olanib?

For some conditions, like early breast cancer and specific advanced ovarian cancer cases, treatment is for a defined period, often up to one or two years. For others, such as metastatic breast, prostate, or relapsed ovarian cancers, it can continue until the disease progresses or side effects become intolerable. Your oncologist will determine the exact treatment plan.

Who makes Olanib?

Everest Pharmaceuticals Ltd., Bangladesh, manufactures and supplies Olanib (generic version of Olaparib). They supply this medication in those countries where their drug administration approves it.

How effective is olaparib?

According to the FDA, olaparib significantly reduced the risk of cancer progression or death in clinical trials for patients with specific gene mutations, such as BRCAm or HRD-positive. For example, in a clinical trial for advanced BRCA-mutated ovarian cancer, it reduced the risk of progression or death by 70%.

How to take olaparib?

Olanib is an oral prescription medication. Take the medication orally twice a day as mentioned in your prescription, with or without food. Dosage and administration can be different depending on the patient’s disease stage or if it has to be administered in combination with other medications. Always consult your doctor before taking any prescription medicine.

How Olaparib Works?

It belongs to a class of drugs known as PARP inhibitors. It blocks the PARP enzyme that helps cancer cells repair DNA damage. When the enzyme is blocked, cancer cells can’t repair themselves and eventually die, while healthy cells are less affected.

How long does Olanib work?

The effectiveness varies significantly depending on the specific cancer, the stage of the disease, and genetic factors. Clinical trials track how long the drug delays cancer progression, a measure known as progression-free survival (PFS).

Is generic Olaparib available?

Yes. Generic Olaparib (Olanib) is produced by several approved manufacturers in India and Bangladesh. Discuss with your oncologist to confirm if it’s suitable for your treatment.

Disclaimer: Information above is not for use as a medical advice alternative; always consult your doctor before taking any prescription medicines.