Niranib 100 mg 30 Capsules

Niranib 100 mg (30 Capsules) is used as a maintenance treatment option in adult patients with ovarian cancer, fallopian tube cancer, peritoneal cancer who are in complete or partial response to platinum based chemotherapy. Niranib works by blocking the enzymes responsible in DNA repair, that signals cancer cells to grow or multiply.

Dosage and Administration

• Start treatment with Niranib immediately after 8 weeks of chemotherapy regimen.
• Take 300 mg Niranib to treat recurrent recurrent ovarian cancer before noon by mouth and continue until disease progression or unacceptable toxicity.
•  To treat advance epithelial, ovarian, fallopian tube or peritoneal cancer in adult patients, suggested doses are 2oo mg by mouth before noon for <77 kg (170 lbs) and 300 mg for ≥77. Start treatment immediately after 12 months of platinum based chemotherapy.

Dosage Modification

Start with 200 mg Niranib

• First reduction is 100 mg
• Discontinue if patient can’t take 100 mg

Start with 300 mg Niranib

• First reduction is 200 mg
• Second reduction is 100 mg
• Discontinue if patient can not take 100 mg

Pregnancy and Lactation

Based on findings from animal studies, research on animal rats shows this statistics that taking Niranib during pregnancy have a risk of fetal harm to fetus. Childbearing potential women should take proper contraception during treatment and for at least six month after treatment. Based on findings from reproductive studies, male patient should also take proper contraception during treatment and should not donate sperm after 3 months of treatment.

Women who are feeding breast to their children are advise not to feed breast milk at least one month after of treatment.

Side Effects

The most adverse side effects are nausea, thrombocytopenia, fatigue/asthenia, anaemia, constipation, vomiting, abdominal pain, neutropenia, insomnia, headache, decreased appetite, nasopharyngitis, diarrhoea, dyspnea, hypertension, dyspepsia, back pain, dizziness, cough, urinary tract infection, arthralgia, palpitations, and dysgeusia.

Storage

Store below 30 degree C and away from light and children.

FAQs about Niranib 100 mg 30 Capsules

What is the price of Niranib 100 mg for 30 capsules?

The price of Niranib 100 mg for 30 capsules are $250.

Who is the manufacturers of Niranib 100 mg?

Everest pharmaceutical manufactures Niranib whose generic is Niraparib.

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