Mezoxia 160 mg (Megestrol Acetate)

Name: Mezoxia 160 mg (Megestrol Acetate)
Brand: Onus Pharma
SKU: 1944
Price: 60 USD
Availability: InStock
Rating: 5 (1 reviews)

What is Mezoxia 160 mg (Megestrol Acetate) used for?

Mezoxia 160 mg (Megestrol Acetate) is used to increase appetite in patients who have lost too much weight due to serious illnesses such as cancer or AIDS. Doctors may also suggest this medication to treat patients with advanced breast cancer and uterus cancer.

How dose Megestrol Acetate 160 mg tablets work in patients body?

Megestrol acetate, the active ingredient of Mezoxia 160 mg is actually a man-made hormone which is similar to progesterone, helps increase appetite and improve weight gain in people who are losing weight due to cancer, AIDS or other serious illnesses. It works by affecting the area of the brain that controls hunger, helping patients feel more interested in eating. In breast cancer and uterus cancer treatment it can help slow down the growth of cancer cells by blocking the effects of estrogen, a hormone that helps tumors to grow.

Dosage and Administration Guidelines

Dosage forms are different for anorexia, cachexia or unexplained weight loss in patients with AIDS or certain cancers such as hormone sensitive cancer like breast cancer and endometrial cancer.

For Appetite Stimulation in AIDS Patients

Recommended initial dose is 400-800 mg orally daily once. Duration of the treatment depends on clinical benefit and until adverse effects are observed.

For Endometrial or Breast Cancer

Recommended dose is 40-320 mg daily orally in a single dose or multiple dose. Treatment may continue for at least two months to assess full therapeutic effect.

Administration Guidelines

Shake the oral suspension well before use.
Take the medicine at the same time every day.
Dosage may depend on the indication, patients weight, response and clinical condition.
It may take several weeks to get the expected result in cancer patients.
Renal or hepatic impairment patients may need dosage adjustment.
Avoid overdosing, it may cause severe side effects.

Are there any medications that interact with Megestrol Acetate?

Megestrol acetate can interact with various medications, substances and components, below are the important to observe.CYP3A4 inhibitors: Ketoconazole, Itraconazole, clarithromycin, ritonavir may interact with Megestrol acetate. These inhibitors can reduce the effect of the medication.CYP3A4 inducers: Rifampin, phenytoin, carbamazepine, St. John’s Wort may interact with the medication and reduce the effect of the medication. Antibiotic Medications: Antibiotics may increase blood sugar if both are taken at the same time and reduce the effectiveness of oral antidiabetic drugs. In this case blood sugar level should be monitored closely for diabetic patients. Anticoagulants: Interaction Warfarin may enhance the anticoagulant effect that increases the risk of bleeding. Frequent INR monitoring is needed for patients. Orticosteroids: There is a risk of adrenal suppression, Cushingoid effects or metabolic disturbances when used together with corticosteroids. Megestrol acetate may interact with hormonal therapies due to its progestin-like effects. Caution should be followed when it is in combination with the Megestrol acetate.HIV medications may increase the level of Megestrol acetate in the blood, in this case monitor side effects like weight gain, fluid retention or adrenal suppression.

What are the contradictions of this medication?

Hypersensitivity to the Megestrol acetate or any of the components in it may contradict in patients with the side effects rash, itching, swelling or difficulty in breathing.
This medication may cause fetal harm or birth defects during pregnancy. It is not recommended to use this medication in pregnancy.
This medication is contradicted if you have an active or history of Thromboembolic disease which may cause deep vein thrombosis (DVT), Pulmonary embolism, and potential risk of stroke. Because Megestrol may increase blood clots.
Avoid taking this medication if you have severe liver dysfunction. Though dosage adjustment and necessary monitoring may reduce the risk of it.
Adrenal suppression risk is not an absolute risk of contradiction but should be used in closely monitoring.

What are the adverse effects of the medication?

Common

Hypertension
Insomnia and mood swings
Rash and sweating
Breakthrough bleeding, change in menstrual flow, hot sweats, impotence, spotting.
Diarrhea, flatulence
Indigestions, nausea
Vomiting
Weight gain

Serious

Deep vein thrombosis
Pulmonary embolism
Thrombophlebitis
Anemia
Adrenal insufficiency

What are the precautions and warnings?

Diabetes mellitus and history of thromboembolic disease
Adrenal insufficiency may occur in patients while receiving or withdrawn from long-term use.
Cushing syndrome was found in patients who were using this medication.
Not to be used as prophylaxis against weight loss
Not to be used for diagnostic test for pregnancy
Consumption of alcohol and drugs may reduce the effect of the medication.

How to use Megestrol Acetate 160 mg in Special Populations?

Breastfeeding women: The Centre for Disease Control and Prevention recommends HIV-1 infected mothers not to breastfeed their children to avoid risking transmission of HIV-1. There is not enough data on breastfeeding women whether they can feed milk or not. Generally, it is not recommended for new mothers to feed their children. Use in elderly patients: Adequate data is not available on elderly patients. Dosage reduction or adjustment for diabetic patients depends on the patient's health condition.

What should I do if I miss a dose or take an overdose?

If you miss a dose take it immediately if it is not too late or close to the next dose. If it is close to the next dose, skip it and consult with your doctor. For overdose you must contact your doctor as soon as possible.

How to store Mezoxia 160 mg?

Store Mezoxia 160 mg at room temperature, away from heat, direct sunlight, and moisture. Keep it safe and reach out to children and pets. Dispose expired medicine safely, do not throw it outside of home, if it comes in contact with animals it may cause problems for them.

Who is the manufacturer and Supplier of Mezoxia 160 mg (Megestrol Acetate)?

Mezoxia 160 mg is one of the significant treatment assistants used to increase appetite in HIV patients or as a therapy for Breast cancer and uterus cancer. It is an innovation by Everest pharmaceutical to treat such lethal diseases. Onus Pharma bridges patients with the medication to meet a new hope and makes sure a smooth delivery to the patients, healthcare professionals and clinics.

Availability and Global Accessibility

This medication is now available at Onus Pharma for global supply. Looking for the best quality generic Megestrol Acetate in Bangladesh? Contact us now for more information we provide

Real time delivery
Affordable price for all renown branded generic medications.
Easy access for global patients and clinics.
Durable packaging for medications
Delivery with trusted global shipping partners.

Looking for other medications that treats advanced or metastatic breast cancer?

Disclaimer: This information is not for any kind of medical use or detecting disease. This is general information that describes features of the drug, accessibility. No patients are recommended to use this as medical guideline or dosage guideline. Follow what your healthcare provider tell you to follow. For more information about patients review of Megestrol Acetate visit their official website.

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