Hertinib 40 mg | Neratinib

Hertinib 40 mg is an alone or combined treatment option for HER2+ breast cancer patients. It is used to treat both, early stage breast cancer and metastatic breast cancer. In early stage breast cancer, it is given alone and in metastatic breast cancer it is given in combination with capecitabine. Being a protein kinase inhibitor, Hertinib works by reducing the growth of proteins that signal cancer cells to multiply. It also helps in slowing down the cancer cells to spread in other parts of the body. By doing that it helps to stop cancer from coming back again.

Dosage and Administration of Hertinib 40 mg

To treat early stage breast cancer

• 240 mg Hertinib daily once by mouth until progression or any severe side effects occurs.
• Reduce the dose if severe side effects like long time diarrhea occurs.

To treat metastatic breast cancer

• 240 mg Hertinib daily once by mouth until any severe side effects happens.
• Continue as cycle each cycle 21 days.

Cycle escalation

• Day 1 to 7: 120 mg daily
• 8 to 15: 160 mg daily
• After 15 days: continue 240 mg Hertinib daily for one year.
• If severe diarrhea happens consult with your doctor and stop taking this medicine until you get well.

Side Effects

The most common and severe side effect in Hertinib is diarrhea. Others side effects are Nausea, Abdominal pain, Fatigue, Vomiting, Rash, Stomatitis, Decreased,  appetite, Muscle spasms.

Pregnancy and Lactation

If you are pregnant or planning to become pregnant, tell your doctor straight away. Your doctor will suggest you. On the other hand if you are already pregnant talk to your doctor and ask whether you should carry the baby or not. Use effective contraception during taking this medicine. Sometimes oral route contraception may not work if you are taking Hertinib. Ask your doctor to suggest right way of taking contraception.

Storage

Store the medicine below 25 C and away from sunlight. Keep medicine out of reach of children.

Cost of Hertinib 40 mg

The cost of hertinib 40 mg for 180 tablets pot is $300(without shipping charge).

See also Parib.