Capivast (Capivasertib 200 mg tablet)

Capivast (Capivasertib 200 mg tablet) is an FDA-approved kinase inhibitor used to treat certain types of breast cancer with a specific gene mutation. It works by inhibiting the enzymes that are responsible for cancer cell growth and spread to other parts of the body.

Capivasertib Mechanism of Action

Capivast is an inhibitor of PIK3CA/AKT1/PTEN kinase, which works by blocking the signaling pathway of blood vessels that helps slow down and stop the growth of cancer cells in the patient’s body.

FDA-approved indications to use Capivasertib 200 mg

Capivast (Capivasertib 200 mg tablet) is approved to treat hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN alterations in adult patients in combination with fulvestrant IV.

Capivasertib 200 mg Dosage and Administration

Recommended dose is 400 mg orally twice a day with or without food. 

• Take Capivast exactly as your healthcare provider tells you.
• Do not change your dose or stop taking without your healthcare provider’s permission.
• Take the medications two times a day at a 12-hour interval, at the same time every day.
• Take the medication 4 days in a row and do not take it for the next 3 days in a week.
• Swallow the tablet with water. Do not chew, crush, or split the tablet.
• Do not take a cracked, broken, or damaged tablet.
• Either take the missed dose within 4 hours or skip the dose and take the next scheduled dose. Do not take a double dose to make up for a missed dose. 
• If you vomit after taking a dose, do not take another. Take the next scheduled dose.
• For women who have not reached menopause or are just starting menopause, your healthcare provider will prescribe a medicine called a luteinizing hormone-releasing hormone (LHRH) agonist to take with Capivast and fulvestrant.

Capivasertib Side Effects

• High blood sugar
• Excessive thirst
• Dry mouth 
• Confusion
• Nausea
• Vomiting
• More frequent urination than normal
• Increased appetite with weight loss
• Dry or flushed skin
• Diarrhea
• Skin reaction

Do not take Capivast (Capivasertib 200 mg tablet) if you have an allergic reaction to it. Consult with your doctor before stopping any prescription medications.

Tell your doctor before taking Capivasertib

• If you have diabetes or high blood sugar
• If you have a rash or other skin disorder
• If you have liver problems
• If you are pregnant or planning to become pregnant
• If you are breastfeeding or planning to breastfeed.
• If you are taking any prescription, non-prescription, vitamins, herbal supplements, or ayurvedic medications.
• Share your medical history with your healthcare provider about previous surgery or long-term disease.

Do these things during treatment

• Monitor your blood sugar regularly
• Tell your doctor to perform liver tests during the treatment if you experience any severe reactions.
• Use proper contraception and an effective birth control method during the treatment and for 4 months after the last dose.
• Avoid drinking grapefruit juice or eating grapefruit during treatment with.

How to store Capivast?

Store Capivast (Capivasertib 200 mg tablet) in the original container, which comes with a tightly closed cap. Keep it out of the reach of children and pets. Keep the medicine at room temperature away from excessive heat and moisture. Keep it in a dry place.

Capivasertib cost in the UK

Capivast (Capivasertib 200 mg) costs a couple of hundred GBP, which is a generic version of TRUQAP, manufactured and marketed by Everest Pharmaceuticals. If it is not available locally in your area, find an authorized distributor. Before purchasing any prescription medicine online, please discuss with your doctor; they may know an authorized distributor. Always be careful when purchasing any prescription medicine online.