Afanix 40 mg 30 Tablets | Afatinib

Afanix 40 mg is used to treat locally advanced or metastatic non-small cell lung cancer. Which is used to treat patients with non-small cell lung cancer who respond to EGFR mutation treatment or have not responded to platinum-based chemotherapy.

Dosage and Administration

Afanix 40 mg is an oral medicine, and patients have to administrate this medicine by mouth. Moreover, patients with NSCLC have to take 40 mg Afanix daily before noon by mouth at empty stomach. This schedule is applicable for those patients, who are diagnosed with non-small cell lung cancer by an FDA approved test. Doses are same for both patients, who respond to EGFR mutation treatment, or have not respond to platinum based chemotherapy. If you miss a dose do not take it within 12 hours till the next day.

Dosage modification

Discontinue treatment with Afanix if any adverse reaction happen. You may resume treatment when all adverse reactions are gone.

Side Effects

The most common side effects of Afanix are

• Diarrhea,
• Stomatitis (30-71%)
• Paronychia (11-58%)
• Increased ALT (10-54%)
• Decreased creatinine clearance (49%)
• Increase alkaline phosphate (34-51%)
• Increased AST (7-46%)
• Decreased lymphocytes (38%)
• Dry skin (31%)
• Decreased potassium (11-30%)
• Decreased appetite (25%)
• Pruritus (21%)
• Nausea (21%)
• Epistaxis (17%)
• Decreased weight (17%)
• Rash/dermatitis acneiform, Grade 3 or 4 (7-16%)
• Increased bilirubin

Pregnancy and Lactation

According to animal studies targeted therapy like Afanix can cause fetal harm to pregnant women. Because the chemical composition of Afanix has the ability to harm the fetus in the worm. So, it is recommended not to take if someone is pregnant. During this treatment women must take proper contraception to prevent pregnancy. Or if someone is already pregnant should consult with doctor before taking this medicine.

In case of lactation, women should not feed breast their children. Because, chemical substance was found in breast milk at who are taking this medicine. They should wait until all chemical appearance are gone from their body.

Cost of Afanix 40 mg

The cost of Afanix is $250 for 30 tablets. And the price may vary over time and manufacturer has the right to change the price any time.

Storage

Store this medicine at 25°C and keep it at original container to prevent exposure to direct sunlight. Keep it away from children.

See also Tagrix 80 mg, non-small cell lung cancer treating medicine.