Afanix 40 mg 30 tablets (Afatinib) – Buy Online in the USA | Uses, Benefits, and Pricing

Afanix 40 mg is used to treat locally advanced or metastatic non-small cell lung cancer. Which is used to treat patients with non-small cell lung cancer who respond to EGFR mutation treatment or have not responded to platinum-based chemotherapy.

What is Afatinib mg?

Afatinib (Afanix) is an oral medication used to treat non-small cell lung cancer with the specific gene mutation EGFR. EGFR means epidermal growth factor receptor. Primarily it is used in lung cancer patients who have been treated with other medications including targeted therapy and chemotherapy before.

Afatinib can be used in combination with other medicines to treat advanced or metastatic non-small cell lung cancer. Here is the general information about afatinb uses, dosage & administration, price and maintenance. 

What is Afanix 40 mg?

Afanix 40 mg is a generic medicine, which has been manufactured by BEACON pharmaceutical. Each Afanix 40 mg contains 40 mg Afatinib. The main benefits of generic medicine is it costs lower than the branded one. That is why it is affordable for everyone.

Afatinib drug class

Afatinib is a kinase inhibitor. It inhibits epidermal growth factor receptor tyrosine kinase. Kinase inhibitors are a type of targeted therapy that works by blocking the action of enzymes called kinases. Kinases are involved in cell growth and cell division. 

Why Choose Afanix 40 mg for EGFR Mutation-Positive NSCLC?

• Clinically Proven Efficacy: Lux lung 3 and Lux lung 8 clinical trials have shown that patients treated with afatinib had better progression than patients treated with chemotherapy.
• Broad Coverage of Mutations: You can choose afanix over other chemotherapy drugs because Afanix targets a wide range of EGFR mutations. It also includes some uncommon variants like L861Q and G719X.
• Convenient Oral Therapy: As it is an oral medication and can be administered at home you can avoid hospital visits for IV therapies.

Afanix 40 mg Dosage and Administration-How to use?

Tablet form 40 mg

Non-small cell lung cancer

Metastatic non-small cell lung cancer

• Patients who have been diagnosed with metastatic non-small cell lung cancer with EGFR mutations and whose tumors are non resistant to other medication should take 40 mg afanix daily by mouth.
• Continue this schedule until disease progression or intolerable toxicity.
• See also administration

Metastatic squamous non-small cell lung cancer

• Afanix is indicated for metastatic squamous non-small cell lung cancer progressing after platinum based therapy.
• 40 mg afanix daily until disease progression or intolerable toxicity.

Administration

• Take afanix at least one hour before or two hours after eating.
• Swallow the whole tablet with water, do not crush or chew.
• Always follow a doctor’s prescription before taking this drug.

Dosage modification

If any adverse reaction happens dosage may be reduced to 10 mg until adverse reaction progression. Consult with a health care professional before modifying your doses. They may examine your condition before dosage modification.

Permanently Discontinue If

• Severe drug induced hepatic impairment
• Persistence ulcerative keratitis
• Confirmed interstitial lung disease
• Symptomatic left ventricular dysfunction
• Severe or intolerable adverse reaction occurring at a dose of 20 mg/day
• Life-threatening bullous, blistering, or exfoliative skin lesions

Coadministration with P-gp inhibitors

• Patients who require P-gp therapy and can not tolerate the regular dose of Afatinib, reduce the dose at 10 mg daily.
• Resume previous doses after discontinuing P-gp therapy.

Coadministration with P-gp induces

• Patients who require chronic therapy with P-gp inducer, increase the daily dose of afanix with 10 mg. 
• Resume the previous doses after 2-3 days after discontinuing P-gp inducer.

Renal and Hepatic impairment

Use caution in case of renal and hepatic impairment while using afatinib. Better you consult with a doctor in renal and hepatic impairment.

Afanix Side Effects and How to Manage Them

Common Side Effects

• Skin Problems: Rash, acne, dry skin, mouth sores, nail inflammation, itching.

• Digestive Issues: Diarrhea, Nausea, Vomiting, Loss of appetite.

• Other: Fatigue, Headache

Serious Side Effects

• Afatinib can cause interstitial lung disease like shortness of breath, cough and chest pain.
• It can cause liver problems including dark urine, jaundice, and abdominal pain.
• Severe diarrhoea can lead to dehydration and electrolyte imbalances.
• Sometimes skin reactions like Stevens-Johnson syndrome and toxic epidermal necrolysis can occur.
• It also can cause corneal disorder and inflammation of the eyes.

Management of the side effects of Afatinib

• Take antidiarrheal therapy and maintain hydration. In severe diarrhoea dosage reduction or interruption may be needed.
• Use emollients and mild corticosteroids if severe skin reaction happens. Dosage reduction may be needed.
• Regular monitor kidney and liver. Be careful of early signs for ILD (interstitial lung disease). 

Afatinib 40 mg price and Where to Buy(Afatinib) Afanix Online

The price of Afatinib 40 mg (Afanix) is $250 and it can be changed. You can buy afanix online from onuspharma.com. Onus Pharma offers you competitive pricing, authenticity guarantee, secure payment and the fastest delivery. Our expert team is available to answer your question and place orders. 

Order Afanix 40 mg (Afatinib) now

To order afanix 40 mg 30 tablets pack contact at our given contact information.

• WhatsApp, Telegram: +8801540071497
• E-mail: onusbd100@gmail.com
• WeChat: Onus Pharma (helpful chinese users)

FAQs About Afanix (Afatinib)

People also ask these questions to know about Afatinib (Afanix)

How does Afanix (Afatinib) differ from other EGFR inhibitors?

Afatinib (Afanix) differs from other EGFR inhibitors in several ways. 

• Afatinib is an irreversible ErbB family blocker, It can bind multiple members of the ErbB family (EGFR/ErbB1, HER2/ErbB2, and HER4/ErbB4).
• Unlike erlotinib and gefitinib, Afatinib binds permanently to cancer cell targets, blocking their signals for a longer time. This may help slow tumor growth more effectively.
• Afatinib is a second generation EGFR mutation inhibitor. It has the ability to inhibit some uncommon mutations like (G719X, L861Q, and S768I). While other inhibitors Gefitinib, Erlotinib and osimertinib have limited ability in mutation inhibition. On the other hand Osimertinib is the third generation and upgraded medication for treating EGFR mutation with less side effects and high efficacy. 

See the table at a glance to get an idea about how Afatinib differs from other EGFR inhibitors

Order Osimertinib 80 mg (Tagrix 80 mg)

Can I take Afanix with other medications?

Your doctor may suggest you take afatinib in combination with other medicines to treat resistant tumors that have no progression after other treatment. Or your tumor got worse after treating it with other medication like chemotherapy. Please do not take other medicine with afatinib without your doctor consultation.

How long will I need to take Afanix 40 mg?

The duration of taking Afanix depends on your health condition or your doctor will tell how long you should continue afatinib. Doctors may suggest you to take afatinib as long as you are getting progression or until your intolerable toxicity. If you want to continue or stop taking afatinib consult your doctor beforehand. 

Is Afanix (Afatinib) Covered by Insurance?

Afanix (Afatinib) insurance coverage depends on your insurance provider. It may vary depending on your suggested doses, location and other relevant things. There are some insurance companies in the USA like Medicare and Medicaid who may make an agreement with you for Afanix if it is prescribed for FDA approved treatment like NSCLC with EGFR mutation.

How can I find out if my insurance covers Afanix 40 mg?

• Contact your insurance provider to check coverage details, copays, and prior authorization requirements.
• Ask your oncologist if they can help by submitting your documents to the insurance company.
• Verify whether Afanix is listed under scheduled medicine or special treatment for a specific period.

Are there patient assistance programs for Afanix 40 mg?

Yes, there are patient assistance groups for Afanix, for that you may contact manufacturers or other groups who are active for patient assistance. You may check online groups who are active on social media like facebook, Instagram or reddit. 

Disclaimer: Always consult your healthcare provider before starting any medication. This content is for informational purposes only and is not a substitute for professional medical advice.