How Niraparib blocks DNA repair in cancer cells, leading to cell death
Introduction: The High Cost of Survival
For patients battling ovarian, fallopian tube, or primary peritoneal cancer, the diagnosis is a heavy enough burden without the crushing weight of “Financial Toxicity.”
Your doctor has likely prescribed Niraparib (brand name Zejula) as a maintenance treatment. It is a breakthrough PARP inhibitor that significantly delays cancer recurrence. However, with the brand-name drug costing upwards of $10,000 to $15,000 per month in the US and Europe, many patients are left with an impossible choice: bankruptcy or skipping treatment.
This guide explains a third option: Generic Niraparib from Bangladesh.
In this article, we will break down the science, the legality, the cost savings, and exactly how you can safely import this life-saving medication directly from the source.
Is Generic Niraparib Real? (The Science)
The most common fear patients have is: “Is this the same medicine?”
The short answer is yes. Generic Niraparib (100 mg) contains the exact same active pharmaceutical ingredient (API) as the brand name Zejula.
Mechanism of Action: Both the brand and the generic work by inhibiting PARP enzymes (PARP-1 and PARP-2). Cancer cells rely on these enzymes to repair their damaged DNA. By blocking them, Niraparib forces the cancer cells to die rather than repair themselves.
Bioequivalence: Reputable generics undergo testing to ensure they dissolve and are absorbed into the bloodstream at the same rate as the original drug.
Why is it Legal for Bangladesh to Make This?
You might wonder how Bangladesh can sell a patented drug for a fraction of the price without breaking the law.
The answer lies in the World Trade Organization (WTO) and the TRIPS Agreement. Because Bangladesh is classified as a Least Developed Country (LDC), the WTO has granted it a special waiver. This waiver allows Bangladeshi pharmaceutical companies to legally manufacture and export patented drugs to other countries where patients cannot afford the brand name.
This means:
It is not a “fake” or “counterfeit” drug.
It is a legally authorized generic manufactured in government-approved facilities.
These facilities often meet WHO-GMP (World Health Organization Good Manufacturing Practices) standards.
Trusted Brands: Beacon vs. Everest
When buying from Bangladesh, you should stick to the “Big Two” manufacturers who dominate the oncology export market.
A. Niraparix (by Beacon Pharmaceuticals PLC)
Reputation: Beacon is the giant of Bangladeshi oncology. They were the first in the country to start exporting cancer drugs globally.
Quality: Their facilities are designed to meet US FDA and UK MHRA standards.
Verification: Beacon boxes often come with a holographic scratch card that lets you verify the authenticity online.
Reputation: Everest is a fast-growing competitor known for high potency and strict quality control.
Focus: They specialize in newer, high-value oncology molecules.
Packaging: Known for secure, tamper-evident packaging.
Feature
Zejula (GSK)
Niraparix / Niranib (Generic)
Active Ingredient
Niraparib
Niraparib
Strength
100 mg
100 mg
Manufacturer
GSK
Beacon / Everest
Monthly Cost
~$12,000+
$400 – $900
Availability
US/EU Pharmacies
Direct Import from Bangladesh
Safety: How to Verify Your Medicine
We understand that buying online requires trust. Here is how you can verify that the medicine you receive is authentic:
The Box: Look for the holographic security seal. High-quality generics do not use cheap, flimsy cardboard.
The Blister: The capsules should be sealed in high-quality blister packs protecting them from moisture.
Batch Number: Every box has a Batch Number and Manufacturing/Expiry date printed on it. You can often email the manufacturer (Beacon or Everest) directly with this number to confirm it was a valid batch.
Prescription: A legitimate supplier will always ask for your doctor’s prescription. If a site sells cancer drugs without asking for a prescription, do not buy from them.
Look for the holographic scratch-pad on the top of the box to verify authenticity.
How to Order Safely
Contact Us: Send an inquiry via WhatsApp or our Contact Form.
Submit Prescription: Send a photo or scan of your doctor’s prescription.
Invoice & Payment: We will send a formal invoice. Payment is usually secure via Bank Transfer (T/T).
Shipping: We use EMS or DHL. Shipping typically takes 10–14 days to reach the USA, UK, or Australia.
Customs: We handle the export documentation to ensure the package clears customs as a “Personal Import” (permitted in most countries for personal medication).
Conclusion
You do not have to fight cancer alone, and you do not have to go bankrupt to survive. Generic Niraparib offers the same life-extending benefits as the brand name, accessible at a fair price.