Mezoxia 160 mg (Megestrol Acetate)

What is Mezoxia 160 mg (Megestrol Acetate) used for?

Mezoxia 160 mg (Megestrol Acetate) is used to increase appetite in patients who have lost too much weight due to serious illnesses such as cancer or AIDS. Doctors may also suggest this medication to treat patients with advanced breast cancer and uterine cancer.

How does Megestrol Acetate 160 mg tablets work in the patient’s body?

Megestrol acetate, the active ingredient of Mezoxia 160 mg, is actually a man-made hormone that is similar to progesterone, and helps increase appetite and improve weight gain in people who are losing weight due to cancer, AIDS, or other serious illnesses. It works by affecting the area of the brain that controls hunger, helping patients feel more interested in eating. In breast cancer and uterine cancer treatment, it can help slow down the growth of cancer cells by blocking the effects of estrogen, a hormone that helps tumors to grow.

Dosage and Administration Guidelines

Dosage forms are different for anorexia, cachexia, or unexplained weight loss in patients with AIDS or certain cancers, such as hormone-sensitive cancers like breast cancer and endometrial cancer.

For Appetite Stimulation in AIDS Patients

Recommended initial dose is 400-800 mg orally daily once. Duration of the treatment depends on clinical benefit and until adverse effects are observed.

For Endometrial or Breast Cancer

Recommended dose is 40-320 mg daily orally in a single dose or multiple doses. Treatment may continue for at least two months to assess the full therapeutic effect.

Administration Guidelines

•       Shake the oral suspension well before use.
•       Take the medicine at the same time every day.
•       Dosage may depend on the indication, patient’s weight, response, and clinical condition.
•       It may take several weeks to get the expected result in cancer patients.
•       Renal or hepatic impairment may need dosage adjustment.
•       Avoid overdosing, as it may cause severe side effects.

What are the contradictions of this medication?

• Hypersensitivity to the Megestrol acetate or any of the components in it may cause side effects in patients the side effects rash, itching, swelling, or difficulty in breathing.
• This medication may cause fetal harm or birth defects during pregnancy. It is not recommended to use this medication in pregnancy.
• This medication is contraindicated if you have an active or history of Thromboembolic disease, which may cause deep vein thrombosis (DVT), Pulmonary embolism, and potential risk of stroke. Because Megestrol may increase blood clots.
• Avoid taking this medication if you have severe liver dysfunction. Though dosage adjustment and necessary monitoring may reduce the risk of it.
• Adrenal suppression risk is not an absolute risk of contradiction but should be used in close monitoring.

What are the adverse effects of the medication?

Common

•       Hypertension
•       Insomnia and mood swings
•       Rash and sweating
•       Breakthrough bleeding, change in menstrual flow, hot sweats, impotence, spotting.
•       Diarrhea, flatulence
•       Indigestion, nausea
•       Vomiting
•       Weight gain

Serious

•       Deep vein thrombosis
•       Pulmonary embolism
•       Thrombophlebitis
•       Anemia
•       Adrenal insufficiency

What are the precautions and warnings?

•       Diabetes mellitus and a history of thromboembolic disease
•       Adrenal insufficiency may occur in patients while receiving or withdrawing from long-term use.
•       Cushing syndrome was found in patients who were using this medication.
•       Not to be used as prophylaxis against weight loss
•       Not to be used for a diagnostic test for pregnancy
•       Consumption of alcohol and drugs may reduce the effect of the medication.

How to use Megestrol Acetate 160 mg in Special Populations?

• Breastfeeding women: The Centers for Disease Control and Prevention recommends that HIV-1-infected mothers not breastfeed their children to avoid risking transmission of HIV-1. There is not enough data on breastfeeding women to determine whether they can produce milk or not. Generally, it is not recommended for new mothers to feed their children.

• Use in elderly patients: Adequate data are not available on elderly patients. Dosage reduction or adjustment for diabetic patients depends on the patient’s health condition.

What should I do if I miss a dose or take an overdose?

If you miss a dose, take it immediately if it is not too late or close to the next dose. If it is close to the next dose, skip it and consult with your doctor. For overdose you must contact your doctor as soon as possible.

How to store Mezoxia 160 mg?

Store Mezoxia 160 mg at room temperature, away from heat, direct sunlight, and moisture. Keep it safe and reach out to children and pets. Dispose of expired medicine safely; do not throw it outside of the home, as it may come in contact with animals, which may cause problems for them.

Who is the manufacturer and Supplier of Mezoxia 160 mg (Megestrol Acetate)?

Mezoxia 160 mg is one of the significant treatment assistants used to increase appetite in HIV patients or as a therapy for Breast cancer and uterine cancer. It is an innovation by Everest Pharmaceutical to treat such lethal diseases. Onus Pharma bridges patients with the medication to meet a new hope and ensures a smooth delivery to the patients, healthcare professionals, and clinics.

Generic Megestrol Acetate price in Bangladesh

The price of generic Megestrol Acetate 160 mg tablets in Bangladesh varies slightly by manufacturer, but the general unit price is around $2-$3 USD per tablet.

Disclaimer: This information is not for any kind of medical use or detecting disease. This is general information that describes features of the drug, accessibility. No patients are recommended to use this as a medical guideline or dosage guideline. Follow what your healthcare provider tells you to follow. For more information about patients’ reviews of Megestrol Acetate, visit their official website.